Dugan O.M.

The Growth Rates and the Accumulation Dynamics of Riboflavin of Ray Fungus Eremothecium Ashbyi Guillier.

The aim of the scientific research was to study the cultural and biochemical characteristics of Eremothecium ashbyi, primarily due to the dynamics of accumulation of riboflavin. The growth rates and the accumulation dynamics of riboflavin in the culture liquid and mycelium of ray fungus Eremothecium аshbyi F340, which is perspective object for receipt of riboflavin by biotechnological method were investigated. Examining the culture E.

Immunomodulating Properties of Probiotics Based on Lactobacteria and Plant Components

Purpose of this work was determination of the immunomodulatory effects of base probiotic composition of lactic acid bacteria based on genus Lactobacillus and the complex probiotic with carbyuloza on an experimental model of intact mice. It was found, that injection of carbyuloza in the probiotic composition increased functional activity of phagocytic system – namely, absorbing activity of macrophages.

The Growth Kinetics of Lactic Acid Bacteria Genum Lactobacillus on Nutrient Media with Different Sources of Carbon and Nitrogen Nutrition

The study assesses the possibility of using biotechnology probiotic soy and glucose-pyruvate culture media, which contain different sources of carbon and nitrogen. When choosing nutrient media, we take into account the end product cost, which can be reduced by decreasing the cost of medic components and simplifying its preparation. We investigate five strains of lactic acid bacteria p. Lactobacillus serving the basis of a new probiotic.

Developing Nutrient Mediums on the Basis of Hydrolysates of the Soybean Flour for Cultivating Representatives of Lactobacillus sp.

The paper considers the second stage of developing the laboratory technology of sanitary sour-milk products on the basis of the soybean flour. It was produced according to the novel national technology ЕСО. The technology is based on the special processing of seeds soybean called “seeds awakening”. As a result of biochemical transformations of matters, outer and inner decontamination of weevils take place.

Selection of Conditions of Submerged Cultivation of Grifola frondosa as the Basis for Development of Biotechnology for Obtaining Medicinal Prophylactic Preparations

The paper investigates the influence of sources of carbon and nitrogen, pH and components of nutrient mediums (beer wort, molasses, corn extract, peptone, extract of yeasts) on the accumulation of biomass and exopolysaccharides under cultivation of higher basidiomycetes mushroom of Grifola frondosa (Dicks: Fr.) S.F. Gray. Crucially, we propose complex nutrient mediums with glucose, ammonium nitrate, corn extract and molasses favorable for biosynthesis of exopolysaccharides and biomass.

Features of Preparation and Fermentation of Soybean Milk by the Representatives

The first stages of development of new laboratory technology sanitary sour-milk products on the basis by an especial mode cultivated seeds of soy have shown. For preparation soybean milk the soybean flour made according to new national technology ЕСО (producer ООО “ЕСО”) has used. The optimum technology of pretreatment of a soybean flour has found with the purpose of subsequent usage as a base for nutrient fermentations mediums. Has established, that milk from soy ЕСО “The present of the sun – Super” as much as possible induce biosynthetic processes for the strains L. delbrueckii subsp.

Morphological and Cultural and Biosynthetic Properties of Eremothecium Ashbyi Guill.

This paper considers the morphological and cultural properties of ascomycetes Eremothecium ashbyi F-340, a producer of riboflavin in various nutrient mediums. We also demonstrate the accretion of fungal biomass, the level of its riboflavin accumulation and the consumption of carbohydrates of nutrient mediums. Through experiments conducted, we determine that using the medium which contains wort in its composition is the most reasonable. Moreover, the riboflavin level in this medium is 2,8 times higher than in other mediums.

Biotechnological approaches to creating and using liposomal and pegylated drug formulations

We analyze and summarize the data on the approaches to creating the system of drug delivery, based on using liposomal and pegylated drug formulations. We also consider the approaches to utilizing the drug delivery system for creating anticancer, antibacterial preparations and immunomodulators.

Obtaining and using of dosage forms based on receptor-mediated endocytosis of biological active substances

This study sums up the data on various approaches to creating targeted drug delivery systems based on the use of receptor-mediated endocytosis. We shed some light on approaches to using targeted drug delivery systems for developing anticancer, antibacterial, and vaccine preparations, as well as in gene therapy.